Key drivers for each region include: for North America, demographics with a high prevalence of atrial fibrillation, ecosystem maturity with well-established healthcare systems, and infrastructure with advanced diagnostic and treatment capabilities. For Europe, drivers include adoption of guidelines-recommended treatments, policies supporting stroke prevention, and investments in research and development. In Asia Pacific, drivers are demographics with a large and growing population, infrastructure development with increasing access to healthcare, and ecosystem maturity with growing awareness of atrial fibrillation and its treatment. Latin America and Middle East & Africa are driven by adoption of affordable treatments, policies aimed at improving healthcare access, and investments in building healthcare capacity.