In the Prescription Orthopedic Drugs segmentation, the Application category is defined by the medical conditions targeted. The largest segment is Osteoarthritis, driven by aging populations and increasing prevalence of degenerative joint diseases, accounting for ~38% of the market. Rheumatoid Arthritis follows, contributing ~27%, with demand fueled by autoimmune disorder treatments and biologics. Trauma-related applications, including fractures and post-surgical pain, represent ~15% of the market, reflecting high usage in acute care settings. Osteoporosis and other musculoskeletal disorders account for the remaining 12% and 8%, respectively, with growth linked to osteoporosis screening and preventive care trends.