The application dimension of Polydatin segmentation delineates three principal end‑use categories: pharmaceutical, nutraceutical, and cosmetics. In the pharmaceutical arena, Polydatin is investigated for its anti‑inflammatory, cardioprotective, and neuroprotective activities, contributing the largest share of market revenue due to intensive clinical development pipelines and regulatory approvals. The nutraceutical segment leverages Polydatin’s antioxidant and anti‑aging properties in functional foods, dietary supplements, and beverages, accounting for a substantial proportion of volume sales driven by consumer health trends. The cosmetics segment applies Polydatin as a skin‑brightening and anti‑photo‑aging agent in topical formulations, representing a niche but growing share as premium skincare brands adopt bio‑active ingredients. Collectively, these applications define the market’s demand structure, with the pharmaceutical sector estimated at 45 % of total value, nutraceuticals at 35 %, and cosmetics at 20 % in the current forecast horizon.