North America dominates the pancreatic cancer therapeutics market growth with a 39% regional forecast share, propelled by rapid adoption of FOLFIRINOX and PARP inhibitors, CMS reimbursement for companion diagnostics, and a dense cluster of Phase III trials. Europe (28%) follows, leveraging EMA adaptive pathways, cross-border real-world evidence platforms, and aging populations exceeding 20% over 65 years. Fastest-growing Asia Pacific (22%) is catalyzed by China’s 2023 accelerated oncology approvals, Japan’s premium pricing for early-access therapies, and expanding private insurance penetration now covering >45% of urban patients. Latin America (7%) benefits from Brazil’s universal oncology tenders, increasing academic-industry consortia, and a 30% rise in screening centers since 2021. Middle East & Africa (4%) shows nascent but accelerating momentum through Saudi Vision 2030 cancer investments, UAE reference pricing harmonization, and the launch of sub-Saharan Africa’s first molecular tumor boards.