Key drivers for each region include: for North America, ecosystem maturity, high demographics awareness, and established infrastructure; for Europe, increasing adoption of Opdivo, favorable reimbursement policies, and growing research investments; for Asia Pacific, expanding patient population, rising healthcare expenditure, and improving regulatory framework; for Latin America, growing demand for cancer treatments, increasing access to healthcare services, and rising economic growth; and for Middle East & Africa, developing healthcare infrastructure, increasing cancer incidence, and growing pharmaceutical market.