Two transformative forces are reshaping competitive dynamics: first, technology shifts toward ultra-short 4- to 6-week DAA combinations and RNA-targeting antivirals that raise efficacy >98% across genotypes; second, regulatory momentum for differential pricing and compulsory licensing in lower-income countries, altering access and supply-chain economics. Competitive intensity is amplified by the entry of high-volume generic manufacturers from India and Bangladesh, compressing prices by 60–80%. From a regional perspective, North America currently commands the largest revenue share (≈42%) driven by high treatment rates and reimbursed therapies, while APAC is forecast to be the fastest-expanding region, reflecting a 9% CAGR as China, India, and Indonesia scale up national elimination programs and adopt WHO-recommended test-and-treat protocols.