The Application segment of the Genetically Modified Mouse market is dissected into oncology, neurology, immunology, metabolic diseases, and infectious diseases. Oncology accounts for the largest share, driven by the demand for pre‑clinical models that recapitulate tumor heterogeneity and therapeutic response, contributing roughly 35 % of total revenue. Neurology follows with 25 % as researchers require mouse models to explore neurodegenerative pathways and drug efficacy for conditions such as Alzheimer’s and Parkinson’s disease. Immunology represents 20 % of the market, reflecting the need for models that mimic human immune system interactions in autoimmune and vaccine studies. Metabolic diseases hold 12 % of the market, supporting investigations into obesity, diabetes, and related metabolic syndromes. Finally, Infectious diseases comprise 8 % of the market, providing essential platforms for studying pathogen‑host dynamics and antimicrobial testing. Collectively, these application sub‑segments form the core of the Genetically Modified Mouse segmentation, each proportionally influencing overall market size through distinct research funding streams and regulatory requirements.