The Ex Vivo Human Skin Models segmentation by types includes full-thickness and split-thickness models. Full-thickness models, comprising epidermis, dermis, and subcutaneous layers, dominate the market due to their utility in assessing transdermal drug delivery and chronic toxicity. Split-thickness models, limited to epidermal and upper dermal layers, cater to acute toxicity studies and irritation testing, offering cost advantages. Full-thickness models represent ~65% of the market, reflecting their complexity and broader application scope. Split-thickness models, while simpler, account for ~35%, serving niche research needs. This typology underscores the market's balance between advanced, multi-layered models and cost-effective alternatives, aligning with varying research priorities across industries.