Segmentation by type differentiates the underlying sensing modalities that power Disease Monitoring Smart Patch solutions. The principal types include Electrochemical, Optical, Thermal, and Hybrid patches. Electrochemical patches dominate the clinical segment because they convert biochemical reactions—such as glucose oxidation or lactate metabolism—into measured electrical signals, delivering high specificity and regulatory approval pathways. Optical patches leverage photoplethysmography, fluorescence, or Raman spectroscopy to capture physiological parameters like oxygen saturation, skin temperature, or pathogen signatures, offering non‑invasive readouts but requiring sophisticated light‑source integration. Thermal patches monitor temperature gradients and heat flux to infer inflammation or fever, providing a low‑cost alternative for large‑scale screening, albeit with limited biomarker breadth. Hybrid designs combine two or more sensing principles, for example electrochemical‑optical multiplexing, to broaden diagnostic coverage and improve data reliability, positioning them for premium pricing and niche hospital contracts. Each type contributes to market size proportionally to its technology maturity, manufacturing complexity, and reimbursement landscape, reinforcing the overall market taxonomy.