The application dimension of the Cabozantinib market is organized around its approved oncology indications, each representing a discrete revenue stream that collectively defines the market size. Renal Cell Carcinoma (RCC) remains the dominant segment, accounting for roughly 45% of global sales, driven by extensive clinical data, strong guideline endorsement, and a sizable patient pool. Hepatocellular Carcinoma (HCC) follows with an estimated 30% share, reflecting rapid adoption in regions with high hepatitis prevalence and expanding label extensions. Thyroid Cancer, primarily medullary subtypes, contributes about 15% as physicians leverage Cabozantinib's multi‑kinase inhibition in refractory cases. The residual 10% comprises emerging and off‑label uses such as prostate and glioblastoma, which, while smaller, indicate future growth vectors. By dissecting these application sub‑segments, analysts can attribute revenue fluctuations to therapeutic success, competitive dynamics, and geographic prevalence, providing a granular view essential for accurate Cabozantinib segmentation analysis.