The Anti-heat Stroke Medicine ecosystem comprises a structured series of upstream, midstream, and downstream activities that collectively transform raw inputs into clinically effective treatments and deliver them to patients. Upstream participants supply active pharmaceutical ingredients (APIs), excipients, and specialized packaging materials. Midstream actors include formulation manufacturers, contract development and manufacturing organizations (CDMOs), and technology providers that integrate stability‑enhancing delivery systems. Downstream entities encompass distributors, healthcare providers, and pharmacies that ensure product availability at the point of care. Value is created through rigorous R&D, regulatory compliance, and supply‑chain coordination, while capture occurs via licensing, reimbursement, and service contracts.