The anti‑VEGF therapeutic segment represents the largest share of the age related macular degeneration segmentation landscape. These agents inhibit vascular endothelial growth factor, a primary driver of neovascular AMD, and are delivered via intravitreal injection. Market analysts attribute its dominance to robust clinical evidence, high reimbursement rates in major health systems, and a mature supply chain that supports frequent dosing schedules. The segment encompasses multiple molecular families—ranibizumab, aflibercept, and off‑label bevacizumab—each contributing to incremental market growth through differentiated efficacy and safety profiles. Pricing dynamics, driven by patent expirations and biosimilar entry, are beginning to moderate revenue expansion, yet the overall contribution remains decisive, accounting for roughly 45 % of total AMD market value.